Plateauing/Increasing HCG - 2nd dose of MTX

Main Board
1

Just wondering if anyone has had a similar situation? Non viable pregnancy of unknown location diagnosed and treated with methotrexate. Needed a second dose which appeared to be effective. Bloods have been declining but then plateauing as the numbers got lower, then last week increased. I was so close as well! Obviously I appreciate this isn’t the place to receive medical advice but I’m just wondering if anyone has had this or similar happened and what happened next? I’m waiting to hear what the next steps are at the moment from the hospital as they have sent the sample away for ‘independent analysis’.

Second dose:

Approx 4500 day 1

3288 day 4

2315 day 7

618 day 14

124 day 21

74 day 28

58 day 35

32 day 42

18 day 49

17 day 56

12 day 63

15 day 70

Thanks for taking the time to read/respond.

2

Dear fiico,

I am so sorry to hear of your ectopic pregnancy loss,

It can be common for hCG levels to plateau during treatment, which can be very frustrating. Occasionally we hear of them rising and falling again, however if they continue to rise, you will need to be reviewed more closely by your medical team.

I am sure you are doing this already, but make sure you are not taking any supplements, especially folic acid, do not drink alcohol or take medications such as ibuprofen and if your levels continue to rise, please seek urgent medical advice with any worsening bleeding or pain or you feel dizzy and unwell.

Sending much love and keeping everything crossed your levels start to decrease again,

Karen x

The Ectopic Pregnancy Trust

Registered Charity Number: 1071811

The EPT is awarded the PIF TICK as a Trusted Information Creator, the UK-wide quality mark for healthcare information

If the information provided here or through the EPT website has helped you, you can donate towards our support services, volunteer, or fundraise to raise awareness.

Further information is available on our website.

Email us: ept@ectopic.org.uk

We provide a call-back support line: 020 7733 2653. We are able to provide support in multiple languages including British Sign Language.

Take a look at our newsletters and subscribe to our mailing list.

Detailed medical information can be found on our website. Please remember online medical information is NO SUBSTITUTE for expert medical advice from your own health care team