Pain on right tube after treatment with methotrexate

I was given two methotrexate shots, on 25th April and on 1st May, and my HCG levels have reached zero on 21st May. I had my period on 9th June and a couple of days after I started having some light pain on my tube. It isn’t bad, I can deal with it with no painkillers, it comes and goes, but it’s there and it is starting to worry me. I took a pregnancy test just to make sure and it’s negative.

Have anyone else felt this? Google tells me it can happen with surgery, but in my case it was methotrexate so I am unsure.

Dear Kety,

I am so sorry to hear of your ectopic pregnancy loss.

Experiencing some pain after an ectopic pregnancy is normal as your body has been through a great deal over the last few months. It is common for women and people to feel pain when the body may be preparing to ovulate and many women and people experience ovulation pain when they did not before their ectopic pregnancy - including myself. You also may have a heightened perception because of the sad loss that you have had to go through. If you find you experience offensive smelling discharge or an increased temperature of more than 37°C or just want to be checked out to be on the safe side, it would be worth asking your doctors to run tests to check for infection.

Your periods can take a while to get back to a rhythm that is more usual for you. I also found that my periods changed for a few months after my losses so it is possible you are ovulating even though you are not expecting to just yet.

If the pain persists, I suggest keeping a pain diary noting when the pain appears, the intensity on a scale of 0-10 and anything that helps the pain eg resting, hot water bottle, paracetamol etc. Visiting your doctors with this information helps them to assess how best to manage your symptoms.

As we are a charity and cannot provide personalised medical advice, I would advise seeking medical advice if you are concerned about the pain, or it worsens.

Sending much love,

Karen x

The Ectopic Pregnancy Trust

Registered Charity Number: 1071811

The EPT is awarded the PIF TICK as a Trusted Information Creator, the UK-wide quality mark for healthcare information


If the information provided here or through the EPT website has helped you, you can donate towards our support services, volunteer, or fundraise to raise awareness.

Further information is available on our website.

Email us: ept@ectopic.org.uk

We provide a call-back support line: 020 7733 2653. We are able to provide support in multiple languages including British Sign Language.

Take a look at our newsletters and subscribe to our mailing list.

Detailed medical information can be found on our website. Please remember online medical information is NO SUBSTITUTE for expert medical advice from your own health care team


EPT Host 20:
Dear Kety,

I am so sorry to hear of your ectopic pregnancy loss.

Experiencing some pain after an ectopic pregnancy is normal as your body has been through a great deal over the last few months. It is common for women and people to feel pain when the body may be preparing to ovulate and many women and people experience ovulation pain when they did not before their ectopic pregnancy - including myself. You also may have a heightened perception because of the sad loss that you have had to go through. If you find you experience offensive smelling discharge or an increased temperature of more than 37°C or just want to be checked out to be on the safe side, it would be worth asking your doctors to run tests to check for infection.

Your periods can take a while to get back to a rhythm that is more usual for you. I also found that my periods changed for a few months after my losses so it is possible you are ovulating even though you are not expecting to just yet.

If the pain persists, I suggest keeping a pain diary noting when the pain appears, the intensity on a scale of 0-10 and anything that helps the pain eg resting, hot water bottle, paracetamol etc. Visiting your doctors with this information helps them to assess how best to manage your symptoms.

As we are a charity and cannot provide personalised medical advice, I would advise seeking medical advice if you are concerned about the pain, or it worsens.

Sending much love,

Karen x

The Ectopic Pregnancy Trust

Registered Charity Number: 1071811

The EPT is awarded the PIF TICK as a Trusted Information Creator, the UK-wide quality mark for healthcare information


If the information provided here or through the EPT website has helped you, you can donate towards our support services, volunteer, or fundraise to raise awareness.

Further information is available on our website.

Email us: ept@ectopic.org.uk

We provide a call-back support line: 020 7733 2653. We are able to provide support in multiple languages including British Sign Language.

Take a look at our newsletters and subscribe to our mailing list.

Detailed medical information can be found on our website. Please remember online medical information is NO SUBSTITUTE for expert medical advice from your own health care team


I wasn’t told any of this at my last hospital visit. This, was IVF and I am scheduling a new visit with the clinic at the end of July. If it doesn’t get worse I will ask my ob-gyn then. I started a pain diary so I can track it. Thanks for the tip and the kind words <3