Unanswered questions

Hello all,

i was diagnosed on 10/24 with an ectopic due to my IUD having moved. My ultrasound showed the embryo to be about 0.6cm in my right tube. Numbers were at 4000 hcg and was less than 5 weeks. Received my first MTX shot that same day and hoped for the best. Day 7 numbers had shot up to 11,000!! Rushed back to receive an ultrasound and no fetal pole nor visible yolk sac. Received my second MTX shot and was a mess waiting for results. Day 4 numbers went down to 7000, day 7 down to 4050 (November 10) !! So I’m relieved that they are going down, but still have questions that are unanswered.

  1. How long have you guys avoided eating folic acid? Dr. told me to still hold off even though numbers are going down.

  2. Forgive me for thinking this at such a stressful moment but the stress is overwhelming and im human…when is it safe to have intercourse again? I’ve read it’s still dangerous because it may rupture but is oral safe or must it wait till numbers are 0???

  3. Has anyone had numbers as high as mine? If so, how long did it take to get to 0. The stress is killing me.

Thank you all in advance!

Dear Mherrera19,

I am sorry to hear of your ectopic pregnancy and loss. It is an overwhelming experience and I will do my best to help.

I am afraid it is difficult to predict how long it will take for your hormone levels reach non-pregnant levels. As we are all individual, our bodies respond differently to the drug and it depends on factors like how high levels reached and our unique physiology. What I can say is that it can take a number of weeks and, while it can take some time, it is not as invasive a procedure as surgery. It is also encouraging that your levels are falling steadily although I appreciate that it can be a drawn out process. Also, in terms of chances of future successful pregnancies, studies do not show a significant difference between treatment routes, whether surgical, medical using methotrexate or expectant management (allowing time for the body to resolve the pregnancy itself).

Whilst being treated with a drug called methotrexate please do not undertake any strenuous exercise or lifting or housework while your hCG levels are dropping. While I do not want to alarm you, there remains the risk of rupture even with low or declining hCG levels. You should not resume exercise until your hCG levels are falling consistently and are in the low 100s. Sadly, there is still the chance of rupture with low or declining hCG levels.

Regarding intercourse, we advise avoiding anything that increases intra-abdominal pressure which includes intercourse. You should take things very easily in the early weeks of treatment and doctors often suggest allowing the body to recover and the first period to arrive before having penetrative sex again - which is around six weeks.

As a gentle reminder, with Methotrexate, you should wait until your hCG levels have fallen to below 5mIU/mL (your doctor will advise you when this is through blood tests) and then take a folic acid supplement for 12 weeks before you try to conceive. This is because the Methotrexate may have reduced the level of folate in your body which is needed to ensure a baby develops healthily. The Methotrexate is metabolised quickly but it can affect the quality of your cells, including those of your eggs and the quality of your blood for up to three months after it has been given. The medicine can also affect the way your liver works and so you need to give your body time to recover properly before a new pregnancy is considered. A shortage of folate could result in a greater chance of a baby having a neural tube defect such as hare lip, cleft palate, or even spina bifida or other NT defects. This is why the “wait” and then taking folic acid for 12 weeks before trying to conceive is so important.

With regards to avoiding food with folic acid, I have added a link on foods rich in folic acid and if you are concerned, you could avoid these until your hCG level has fallen below 5mIU/mL.

https://www.google.co.uk/search?q=food+ … e&ie=UTF-8

Sending much love,

Karen x


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Hiya… I had an ectopic treated with MTX in September… I was told to wait for folic acid until I was “not pregnant” which I believe is anything under 5… been eating it like mad ever since and taking supplements every day!!

My numbers were nowhere near as high as yours (990 being my highest at approx. 5 weeks). I don’t think the numbers mean anything and it just depends on the doubling every 48 hours… one person may be at 500 whilst the other is at 15000 on the same week of pregnancy… from my MTX Shot (26th September - hcg 915) I got down to 4 by 16th October and was discharged…

They advised against sex until after this time and to obviously use protection for at least 3 months before trying again! I’m assuming oral is all fine and dandy lol :slight_smile:

Hope this helps x

Gem-Lea,

Wow, the MTX worked so quickly for you!! i had numbers drawn yesterday and they are down to 2000, seems like they are going down at a 50% rate so hopefully by Dec 1 I’ll be at 0!!

I’m going crazy without regular foods that have folic acid! Luckily i found gluten free foods have no folic, but there’s only so much of the same a girl can eat.

I’m assuming oral is fine too since there’s no intrabdominal pressure lol. Hopefully. I’ll weigh out the desperation and risks.

EPTHost,

Thank you so much for all the details. I’m being careful to avoid strenuous activity.

You provided me with a lot insights. Let’s hope this road to recovery is fast!