Dear Elizabeth,
I am so sorry to hear of your ectopic pregnancy loss, it can be extremely overwhelming and you have friends here who understand.
Following methotrexate, the hCG level often rises on the day four blood test because the action of methotrexate is not instantaneous, so the cells will have continued to divide for two or three days after the injection was given, and some cells release more hCG when they start to disappear. Your doctors are looking to see a drop in your hCG value of at least 15% between days four and seven. If there has not been a 15% drop, this is when the doctors will consider a second dose of methotrexate or surgery.
I know it can feel like a long drawn out process but methotrexate is used as it isn’t as invasive as surgery.
I too bad methotrexate, my hCG levels rose on day 4 and then slowly declined over a number of weeks. I cannot be more precise of levels and how long it took for me as it was 14years ago and my memory is a little hazy. I went on to have 2 successful pregnancies, so.I hope this gives you some hope.
We have more information on our website about methotrexate treatment, how to help the medication work, what not to do and when to seek additional medical advice, which I have posted here
https://ectopic.org.uk/treating-an-ecto … thotrexate
Do not hesitate to lean on us for as long as you need,
Sending much love,
Karen x
The Ectopic Pregnancy Trust
Registered Charity Number: 1071811
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